z-Movi
Cell Avidity Analyzer
The z-Movi® is a unique instrument that measures the avidity between immune cells and their targets, enabling you to identify the most potent immunotherapeutic effector cells. This new technology provides you with predictive, reproducible, and fast high-throughput results at a single-cell resolution without compromising cell viability. All within a compact little box that easily fits inside the flow hood for sterile and safe sample handling.
(1) Target cells or ligands are immobilized on the surface of the chip and left to incubate with cells of interest.
(2) By applying varying levels of forces, the cells of interest can be distinguished based on avidity
(3) Low avidity cells require less force to be separated from their interacting targets, while high avidity cells remain bound. Repeating this process with a gradually increasing force allows screening and sorting cells based on their avidity.
(2) By applying varying levels of forces, the cells of interest can be distinguished based on avidity
(3) Low avidity cells require less force to be separated from their interacting targets, while high avidity cells remain bound. Repeating this process with a gradually increasing force allows screening and sorting cells based on their avidity.
Single-cell resolutionMeasure the binding strength between every effector cell
Avidity measurementDirect measurement of binding avidity
High throughputAnalyze avidities of up to 400 cells in a single run
Non-invasive acousticsLeave your cells healthy and viable.
CompactSmall enough to fit inside a flow hood
Fluorescence cell imagingDistinguish and follow individual fluorescent effector cells
